Yarimsintetik antibiotik.
Roksitromitsin eritromitsinning yarimsintetik hosilasidir.
Roksitromitsin kontentratsiyasiga va bakteriya turiga qarab, bakteriostatik yoki bakteritsid ta’sir ko‘rsatadi.
Asosiy ta’sir mexanizmi, bakteriyaning oqsil sintezini bostirilishi bilan bog‘liq.
Antibakterial ta’sir kengligi
Aerob grammusbat bakteriyalar: Streptococcus spp.
(shu jumladan Streptococcus pneumoniae, Bacillus cereus, Corynebacterium diphtheriae, Listeria monocygenes); aerob grammanfiy bakteriyalar: Bordotella pertussus, Campilobacter coli, Campylobacter jejuli, Gardnerella vaginalis, Haemophillus ducreyi, Helicobacter pylori, Legionella pneumophilia, Moraxella catarrhalis, Neisseria meningitidis, Pasteurela multocida; anaerob bakteriyalar: Actinomyces spp., Bacteoides urealiticus, Clostridum spp.
(Clostridum difficiledan tashєari), Eubacterium spp., Peptococcus spp., Peptostreptococcus spp., Porphyromonos spp., Prevotella melaninogenica, Propionibacterium acnes larga nisbatan faol.
Preparat, shuningdek, Borrelia burgdorferi, Chlamydia pneumonia, Chlamydia psittaci, Chlamydia trachomatis, Cryptosporidum spp., Mycobacterium tuberculosis, Ricettsia conorri, Ricettsia richttsii, Toxoplasma gondii larga nisbatan faol.
Preparatga Haemophilis influenzae, Neisseria gonorrhoeae, Vibrio cholerae, Bacteriodes oralis, Mycobacterium avium complex, Mycoplasma pneumoniaye, Ureaplasma urealyticum, Enterococcus spp., Staphylococcus aureus (metitsillinga sezgir), Staphylococcus epidermidis (metitsillinga sezgir) larga o‘rtacha sezgir.
Preparatga Bacteriodes fragilis, Mycobacterium homunis lar turg‘un.